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That is, stimulation of CD74 with exogenous MIF might result in an extreme inflammatory state, as MIF is effective at stimulating CXCR2 and CXCR4 receptors Along with CD74. CXCR2 and CXCR4 receptors when activated promote inflow of neutrophils and lymphocytes, respectively (63, sixty four). Fig. 4: Diagram with the human MIF gene demonstrating its